I am ready for TRUTH, I can handle the TRUTH

I am pretty new here and pretty new to HI-FI so please be patient with me. I am learning pretty quick.

I have been afraid to ask this question...

What effect does having a 65 Inch HD projection
TV in between main's have?

I am very limited for room so i didnt have to many options. Room is rectangular. The mains, TV and center (on top) are placed at a 45 degree angle (left side corner of room) with approx a 10sf triangle behind TV. The left main is very close to LARGE TV and the right main is a few feet from TV. The sub is off in right corner. The speakers are thin Infinity floorstanding. The sub is a Velodyne 15.

Although im open to room placement changes this
question is more of what kind of effects can having
a large TV in between mains have? I listen to mostly
2ch probably 70% and 30% DVD-A and TV/Movies. And
I listen to music at pretty loud levels the highest
being 110db's average probably 80db.

Appreciate any input...