How Big is Too Big?

As the resolution has increased for video monitors, I have been using a 32" 1080 HDTV for a computer monitor, which seems to work just fine.

In fact, now that I am becoming a bit far sighted, I am wondering if I might even use a BIGGER HDTV for both cable TV and PC applications, streaming video etc etc.

Have any of you experimented with using one or more 1080 screens, 32" or more?

How about an array of screens - 40? 46?

Thanks for any ideas.