The distance from the front wall is going to effect the mid and upper bass/lower midrange. If the face of the woofer is three feet from the front wall, the distance to the wall and back is 6 feet, that is the wavelength of about 185 Hz. Thus 185 Hz and the frequencies around it are going to be reinforced. As you move the speaker closer to the front wall the reinforced frequency increases, as you move away the reinforced frequency decreases. At five feet it is about 100 Hz. Other frequencies are attenuated. None of this is good. Sound absorption on the front and side walls is very important but it is only effective above 200 Hz at best. If you could set up the speakers 10 feet from the front wall you could reinforce 55 Hx. 28 feet would reinforce 20 Hz. All this is impossible in residential situations.
All the above is the reason that digital room control is so important particularly in the bass.
Any other changes in sounds quality with speaker positioning depend on the timing of reflections which depends entirely on the room. These reflections effect fine detail and imaging. If reflected sound can travel 100 feet before reaching your ear you hear an echo. Thus the more sound absorption you use anywhere in a room the more you are going to decrease the likelihood you will hear an echo, which IMHO is a good thing as the echo was not in the recording. Some people actually like echoes as they add a false sense of spaciousness. All the echoes of the venue where the recording occurred are on the record. Studio recordings frequently have echo added to them to create dimension. Live recordings generally do not need it.
Sorry for preaching.