Before tackling the audio interconnects, disconnect any video or ethernet devices. An RCA out to a TV that has a satellite cable in or an HDMI from another device plugged in elsewhere can be the problem. The additional shielding on “better” ethernet cables, like CAT-7 instead of CAT-6, can also be the problem. Ethernet is itself by design fine. But the shielding on a cable can be the problem...
Re: bug zapper comment above... yes, keep it off the house ethernet ;-)