I can attest to Oldtex's statement about tube life being negatively affected by heating and cooling the tubes' elements every time you turn your unit on or off. I use a tubed preamp with fairly good NOS (new old stock) Mullard tubes. I have left my preamp on 24/7 since I bought them. I just replaced the tubes with a new group of 4 tubes. The orginal tubes lasted 6 years. I think this proves that leaving tubes on 24/7 can extend tube life in atleast 1 selective case. I would say that leaving tubes on will not negatively affect tube life in my setup.
I'm going to continue leaving my preamp, and class d amp, on mainly because it sounds good immediately instead of after a 1-2 hour warmup. The class d amp requires zero warmup but I leave it continually on due to convenience and the fact it uses so little juice.
Of course, YMMV.
Tim