As you move up the Dynaudio line up there is more refinement. The Focus 160 will be a bit punchier and tipped up in the highs vs Contour or Confidence. Some will say the Contour and Confidence will sound a bit laid back in comparison.
Me personally I like the punchier tipped up sound for about an hour or so (wow factor). The longer I listen to them the more I dislike them. Again my opinion. I owned the C1 and later the C1 sig's for several years. To me they sound more natural and balanced.