You have to ask yourself, do you really think the sound stage, which is almost all a factor of recording and speaker/room interaction, would magically collapse due to some exceedingly low level interaction between a cable and the floor?All the subtle information we look for with our ears, in a recording, is low in level..so yes..I would expect that the subtle and easy to disturb high slew rate impossibly intertwined micro signals involved in our limits of human resolution ..might benefit from some careful handling.
The gross and subtle signals are also paired up in the sense of requiring perfected micro timing and long term accurate micro timing differentials between them for our hearing limits to be fully engaged...so yes..... there would be a difference between the two with the cable suspended vs just laying on the average floor.
All things being equal, as in good system, gross mechanical and complex LCR differences between floor and suspended, good hearing in the individual that is part of the experiment, and so on.
All things are not quite equal with respect to one person and their system, vs another.