Absolutely, yes.
Being in lightning alley, if you will, I will even unplug the system if I am out for the day and I know that storms are on the way. Rain, no. Storms that produce lightning, yes.
Having actually heard two of my amps literally being sizzled while being broadcast over the speakers, as they were sizzling is a sound I wish on no one. That particular storm snuck up on meor just popped up out of nowhere, and I had just gotten out of the shower, as I was listening to music.
That one strike took out two of my amps that I had just had revamped a week or two earlier. Grrrr.
Tom