I play the drums. Admittedly I am just getting into high-end audio, but my uncle has been an enthusiast for as long as I can remember. He has a dedicated listening room and often invites me over when he changes things around. He usually plays a track that I am familiar with, and I can tell you that I absolutely hear differences between cables, amps, etc. I typically pay closer attention to the percussion instruments, and he has definitely had set-ups that sound very lifelike.
