Some folks have claimed that they can hear a difference in their speaker wires after breaking them in by using them in an AC load for 100 uninterrupted hours. I haven't tried this yet, but I am planning to when I do my wires.
I did a comparison using a single pair of #10 AWG wires going to one speaker, and an 8 pair twisted #18 AWG shielded Belden cable for the other, and there was a significant difference noticed with the multi pair cable. I tied all of the black wires from each pair together, and all of the white wires from each pair. Everybody who listened could tell the difference when the left and right channels were selected seperately.
I did a comparison using a single pair of #10 AWG wires going to one speaker, and an 8 pair twisted #18 AWG shielded Belden cable for the other, and there was a significant difference noticed with the multi pair cable. I tied all of the black wires from each pair together, and all of the white wires from each pair. Everybody who listened could tell the difference when the left and right channels were selected seperately.