Direct Line Question

It shouldn't make that much difference, especially if you run each in its own conduit. If it's Romex, you might want to keep them about 6" apart.

Just don't pull speaker line or video line through the same holes.

Should the Romex be twisted to cancel interference? How many twists per foot? Twisted which way, counter clockwise north of the equator?, or would that just magnify the Coriolis effect ?

Do Coriolis forces apply to electromagnetic energy? That's a new one on me. Twisting the wire would help reject RFI, but I don't think Romex will twist enough to do that very well. People do twist separate insulated conductors before pulling them thru steel conduit. That's the best if RFI is a problem where you are. I've also pulled Romex thru conduit (I think because the Romex was on sale ;-)

Just joking about the Coriolis effect....

Ah the Coriolis Effect. This is why I always have my speakers facing west. Once the sound leaves the speaker it gets to me faster. :-)