Well AKGWIZ a 17x 32 room, with a "half" vault of 13 ft, and the rest 9ft ceilings, is a pretty clean slate to start with. Great for long standing frequencies.
With a room that size there are numerious full range speakers that'll shine, so IMHO - kiss (keep it sweet & simple). The fancier the plumbing the more likely you'll clog the drain. So why monkey with subs if you don't have to.
Lots of files like their Maggie's, & they have their pro's, but for my ear I'd choose the big Martin Logans. Both brands love power amps, I'd say you'll get considerably more speaker from the Logans. But there's also the school of thought that lower power amplifiers sound better, for example the Classe' DR3 VHC, Mark Levinson ML-2, Krell KSA-50S, Valve Amplification Company PA90D in triode, or the Wyetech Topaz 572.
These amps will run high efficiency speakers with a nominal impedance of 8 ohms all month. Offering transparency, attack, articulation, headroom, timbre and a soundstage that dazzles, matched with the proper speaker .... to kill for.
Think Avantgarde, Tannoy Westminster or even Canterbury's, Volti Audio Vittora's, and don't forget the humble Klipsch K-horn.
To get the most out of any of these combinations not only requirers, but demands outstanding upstream components (garb in garb out), that said, I'm sure you already knew that.
Enjoy the voyage.