Comfortable by good sounding headphones?

Due to lifestyle I listen to my main system only on weekends but I find myself wanting to listen weekdays at night. Purchased a pair of Grado 325 phones and Melos SHA 1 headphone amp. The amp is exceptional but I find myself only listening for an hour or so because of ear fatigue with the Grados. I like the sound of the Grados but really don't care for the fit. Thinking about the Sennheiser 600 or 650 but with their more open design not sure if the music could be heard by others( I listen at normal volumns) and concerened about comfort. Any comments or suggestions for other headphones appreciated.