Nagel, great points you've made. Let me say this and maybe it will help.
I have tried Cardas Clear Reflection interconnects with my system paired with cheaper $200 speaker cables and was disappointed.
I then borrowed a pair of Clear Reflection Speaker cable and it sounded WAY better - BUT, it seemed to not be quite as dynamic as I'd hope and there could also be a little to much harshness (occasionally, not all the time) on the top end. I spoke to someone at cardas who told me that the reflection cables were designed for low efficiency speakers and that he wouldn't reccomend it for klipsch high effeciency cornwalls.
Then i started looking into the audioquest stuff because i wanted more dynamics. But what you said about losing top end, that doesn't seem like something I want.
You mentioned you liked cardas - what cardas interconnect and speaker cable would you suggest with these components?