Lots of great choices mentioned. You may need to consider a large monitor or mid size tower to fill that size room, but if you’re limited to a smaller monitor: Often overlooked but worth investigation are the Aerial Acoustics 5t, Stereophile Class A rated and also super sexy in Ebony finish, ~$3K used if you can find them.
Candidates for best speakers in the $2000-5000 market
I’m asking for listeners’ experience in this bracket, buttressed by reviews and/or data; I am not a fan of "whatever sounds good to you." Ultimately, yes, that will be the case. But in getting to that point, I’m looking to benefit from the advantage of a thousand pairs of ears rather than mine alone. Those ears can include the inanimate. Thank you.
My experience has included my own Elac 403, Elac 407, and Dynaudio Special 40. Auditions have included various Sonus Faber, and Magico. All of this is in preparation for justifying the leap for an Electa Amator lll or its equivalent. But that’s for another day, another forum.