You should check with the manufacturer, but I beleive that you can. We used a Crown amp for many years using just one channel without harming the amp in question. More importantly however, I suggest that you choose an amplifier by listening to it and then deciding how it might work in your particular situation rather than choosing one merely for its "spec power" rating. If the first watt of a particular amplifier sounds bad, why in the world would you want 300 more? Just my 2 cents worth. Happy Listening,