boomerbilloneBoomer make a good point that could happen to something else, if using linear amp/s for the mids/highs and Class-D for the bass. As many Class-D’s don’t have their negative (black) output at ground potential. Linear's do.
Just to save you from blowing something up, be sure the amps are not connected to a common ground at the speaker end.
It may rarely happen but could, if the speaker designer was asleep.
When you remove the speaker bi-amp/bi-wire bridging links at the back of the speaker. Even after removing them make sure with an ohm meter that the two negatives (blacks) are still not connected together inside (meter needs to show open circuit). As if they are you’ll need to break the common trace inside the speaker that connects them on the xover. Otherwise the linear amps black terminal will give ground potential to the black terminal of the Class-D, and BOOM! could happen!
Cheers George