If you find there is nothing wrong with the amp, it could be pre clip warning.
The Mirage M1’ are a great speaker and this 4B should be fine, the M1’s do have a nasty 5ohm combined with -45 phase angle at 60hz but the 4b should handle this.
http://www.stereophile.com/content/mirage-m-1si-loudspeaker-measurements#PGAwhPPKQTyDfY5g.97
The Bryston is dc coupled, I think maybe you could be getting warp frequencies or subsonic rumble arm resonance coming through from your t/t phono stage setup, I don’t know what bass mode means on the Holman pre, but it looks like it maybe a rumble filter, see if that cures it.
If that’s no good, then try cd player and a different preamp see if it cures it.
Cheers George