Alright i have never heard the bryston amp but i do own the nuvista amp. I also own the plinius Sa - 250 Mk. IV and the mark levinson 380. preamp. The nu vista m3 is better than these 12,500 dollar top of the line well chosen components. I have a/b'd the two exstensively and can definitely say that if i had the choice between the two i would take the M3. Now i am not saying that it is better than the combo in every way. The bass is not as pucnhy, powerful or strong and the soundstage is not as wide. The detail and musicality of the M3 is better however by a large margin. I really think you should get the M3 it is one of the best bargains i have ever seen at its retail price. I have done a lot of research on it and it really essentially is in almost every way slightly better versions of the nu vista 300 and the nu vista preamp in one box. So i really see the list price of the M3 as 7500.00 and not 4500.00 because it really is a 7500.00 dollar component. BTW where did you find an M3 these days and how much are you paying for it? Thanks - Ian