break in question

>> it has been suggested to me that the process of breaking in a cable really entails "acclimating" the link between components to a particular cable. <<

I don't think I'd lose too much sleep over this. Once the cable has had several "heat up" and "cool down" sessions (basically a mechanical settling of the cable), it's hard to imagine *why* it should make any difference what is connected on either end. It's not like the electrons need to feel comfortable with the new equipment...

is it advisable or necessary to repeat the break in process when changing the component interface

Hardly. However, it has been rumoured that a wire, left unconnected for a long time may need to "re-settle".
Admittedly, however, IME it takes very little time to "settle-in" a wire EXCEPT for the tonearm cable (which takes longer). Cheers