Yes, you can do it, but if you have decent jumpers like:
https://www.amazon.com/AudioQuest-Direct-Silver-Plated-BiWire-Jumpers/dp/B0057FK8RS/ref=sr_1_3?dchild=1&keywords=audioquest+jumper&qid=1597306205&sr=8-3
(they also come in gold plating)
then why do you want to change it? Idea behind biwiring is that resistive and inductive impedance of the wire creates (with amp's output impedance) divider for back EMF, since crossover filter is not perfect (interaction between speakers). I know, from this forum, that it helps with some speakers and makes absolutely no difference with the others. It doesn't hurt to try. I have three way speakers with jumpers between tweeters and mid range and shotgun cable connecting it and bass section to amplifier.
https://www.amazon.com/AudioQuest-Direct-Silver-Plated-BiWire-Jumpers/dp/B0057FK8RS/ref=sr_1_3?dchild=1&keywords=audioquest+jumper&qid=1597306205&sr=8-3
(they also come in gold plating)
then why do you want to change it? Idea behind biwiring is that resistive and inductive impedance of the wire creates (with amp's output impedance) divider for back EMF, since crossover filter is not perfect (interaction between speakers). I know, from this forum, that it helps with some speakers and makes absolutely no difference with the others. It doesn't hurt to try. I have three way speakers with jumpers between tweeters and mid range and shotgun cable connecting it and bass section to amplifier.