Between a Node 2i and DAC: Does Coax cable quality really matter?

@rareace, the iFi does improve the SQ in several ways, music has more weight, wider deeper soundstage, more dynamic. I'm also using a Swagman Labs LPS.

What's the difference between  iPurifier2 and the first generation?

Yes, you will hear a difference between cables. Nobody can say for sure if there will be an improvement. If you feel an upgrade is in order then audition other digital coax. Order from dealers who offer a trial period. 

I auditioned quite a few S/PDIF cables, also returned a few. Finally I found a cable that significantly improved my digital setup.

I have chord Qutest so jitter not much of issue.
I used iFi on older DAC and thought it was a subtle improvement.

Without a LPS you don't get the full benefit of the iPurifier. I tried it both ways, the wall-wart had no balls.

rarerace, I’m curious. I’ll take a look at the website.
One flaw with the 1st generation was that the unit kept falling off the Dac RCA input. Finally customer service sent me another replacement and said they were sure this one would fit.

Rarerace, I learned that ver.2 has improved noise reduction so I'm going to contact iFi.