Surely it will all be relative; with 86dB speakers you are going to want a KT88 based amp if you are using valves; with 106dB horns you are going to want 300B. And with my 93dB speakers ... well, I'm in between all these possibilities.
A friend brought round his Unison Research S2K a couple of weeks ago. A budget SET amp but a very nice design. He had a pair of 6550s in and the sound was extremely immersive, a great sense of space filed with micro-detail. It had a wonderful way of getting the inner detail of a saxophone (the close focus on Coltrane's vibrato was new to me). But central voices tended to be lost a little behind the whole soundscape. Then we switched in a couple of my KT88s. Suddenly the voices were central and clear, but all that lovely spatial immersion and the inner detail was lost. I don't know if that is a comment on my particular KT88s, or how that amp works. It was supposedly designed for KT88s, but we were clearly missing something when we took out the 6550s.