I would start by eliminating anything described as "computer speakers". Part of the mass downfall in the quality of reproduced music - in addition to the obvious culprit of MP-3 -- is the idea that you can get "great" "amazing" etc sound from a pair of $59 speakers at CompUSA. You cant.
Once you get past that hurdle, you can pretty much have whatever you like and only the sky is the limit.
For a nearfield application like sitting at your desk in front of a screen, you might also consider powered studio monitors. Then, you could run a line level out from a good sound card straight into the speakers.
There are many manufacturers in this space. For sitting on top of my piano, I have a pair of Genelec 1029 A's (?) which have an amazing amount of punch and detail in a nearfield set up and they are built like tanks.
Good luck.
Once you get past that hurdle, you can pretty much have whatever you like and only the sky is the limit.
For a nearfield application like sitting at your desk in front of a screen, you might also consider powered studio monitors. Then, you could run a line level out from a good sound card straight into the speakers.
There are many manufacturers in this space. For sitting on top of my piano, I have a pair of Genelec 1029 A's (?) which have an amazing amount of punch and detail in a nearfield set up and they are built like tanks.
Good luck.