I didn't spend much time using the amps in mono mode, so I haven't drawn conclusions about that configuration. Mono sounds a little different than Stereo, but that difference is smaller than when ‘Using’ two stereo amps in one-channel mode.
My speakers have a sensitivity of 88 dB (B&W 805 D4 Signature) and I never see the protection lights on the amp(s) when running in Stereo mode, so more testing in Mono is needed.