Always select speakers first. If you are drawn to the sound of Vandersteen loudspeakers then you should probably buy them.
Other speakers that are like Vandersteen are Devore Fidelity which are also liquid sounding speakers, Other speakers you might like Gallo Acoustics 3.5 soft top end an and a big soundstage, not as full bodied as the Vandersteens and the Gershman speakers.
Stay away from B&W, KEF, Monitor Audio, Wilson, Magico, and most any speaker with a metal dome. I know Vandersteens use a metal dome tweeter but the speakers are voiced on the warm side while most metal domes sound much more forward.
Also check out Harbeth, and Spendors, and Dynaudio.
I would always pick the speaker first and then build the system around it no matter how cool you might think the Ayon is unless you can find the right synergy with the loudspeakers I would walk away from the amp and find a dealer who can setup the speakers with the amps you like and then you will know what the system will sound like.