I would sure hope there’s a huge difference. I took home a LS 25 MKII when I was last shopping for a preamp, and that preamp didn’t do much for me… didn’t do anything bad but I felt the ModWright LS 36.5 was more engaging at least in my system. I have not dragged home an ARC Reference preamp but have listened to them a lot at local dealership and even there they sound special. I’d be surprised you’d be disappointed if you make the change.