i don’t use slugs in place of fuses, although my amplifiers come with thermal couplers instead of fuses. which eliminates the noise factor there. and my preamp is battery powered so no fuses there either.
what i did do relevant to slugs is my Equi=Tech 10WQ Isolation transformer wall panel has GFI’s for each circuit. this 375 pound wall mounted isolation transformer is just for my system circuits. my barn has a separate 'dirty power' 100 amp panel for all other uses.
https://equitech.com/proiducts/wall-mount/10wq/
i had my electrical contractor remove the 10 GFI’s and a straight pure copper wire is put in place for each circuit. since my room is in a separate building and like a commercial studio i got him to do it.
GFI’s are even noisier than fuses.