If I had a room that size and could get a ways away from the speakers and liked to rock and roll (which I do) I'd buy a big pair of Klipschorns (used) a moderately powered tube integrated or tubed CD player and call it good. Keep it simple and try some Paul Speltz anti-cables and spend the rest of the money on music or tuning the room. There are many integrates that would fit the bill as well as CD players. Maybe a modified Jolida with a Creek integrated? If you have more money move up the food chain, the options are unlimited. No, I don't use Klisch speakers but have had them in the past, but I didn't have the room to let them breathe and/or get some distance from the horns. Put em in the corners and rock...or whatever your tastes run to.
Another option (if you are strictly going digital) would be to add a DSP preamp (like a Tact) and a moderately powered tube amp. This way you wouldn't have to spend any money on room treatments.
One other thing that would work with this would be a passive preamp like the Placette with a tube amp and CD player. The possibilities are unlimited, but big speakers in a room that size are a necessity in my opinion. My $.02.
Another option (if you are strictly going digital) would be to add a DSP preamp (like a Tact) and a moderately powered tube amp. This way you wouldn't have to spend any money on room treatments.
One other thing that would work with this would be a passive preamp like the Placette with a tube amp and CD player. The possibilities are unlimited, but big speakers in a room that size are a necessity in my opinion. My $.02.