Never dived into the 45 vs 33 question - but I always found 78's were the best compared to a 33 of the same song. I assumed this was because faster speed = longer groove = the ability for more information to be captured in the cut. Applying that logic to your question, 45's ought to have the edge.
@aewarren Agree on the orange disc. Bought a Soft Machine Vol 1 to replace my 30 year old copy - amazing packaging compared to my original - working dial and all. Then, I pull out the record to see colored vinyl. Somebody need to tell them to stop doing this - just stop.