I've run my 2ceSigs and 2wq sub with both a ARC VT-60 (50 wpc) and now a McCormack DNA-225. Both amps perform well in the midrange in my set-up. I prefer the significantly better mid and lower base control with the DNA-225. Also, based on my experience, I highly suggest playing around with speaker placement. +/- a couple of inches can make a big difference - in my case, after I switched to the DNA-225, I moved my speakers out from the wall an additional 2 inches or so (this after following Vandersteen's set up instruictions to the letter)... and WOW, images floating and everything sounds better top to bottom. I really love my DNA-225.