Sorry to get here late however I wanted to mention that I am using an Ayre QB-9 DSD DAC and have had luck with tweaking the sound beautifully. I've added an XLR tuning stick from Akiko Audio to my DAC left XLR output and an Akiko 3D tuning chip on top of the DAC, in the center and towards the back (at first the 3D tuning chip was overwhelming but I have now found that an entirely different placement from my original choice makes this DAC sing beyond my expectations). I switched out the DAC stock fuse with a Synergistic Research Black fuse and added two Akiko fuse tuning chips as well. I've also added an Akiko USB tuning stick to my MacMini. The difference is remarkable and I am no longer up sampling. I've found no up sampling to be both unnecessary and preferable. I also use Audirvana Plus 3.
For those who are totally opposed to tweaking, I completely understand but if you have no objections towards tweaking, the Akiko products, with patience and careful placement, work wonders .