Most achingly-beautiful music

Lucinda Williams' "Essence"

Barber's "Adagio for strings". "Wolf Eyes" by Paul Winter,I have played this at some important dog's funerals,yes,I'm crazy but if you have ever loved a dog I bet you'll tear up when you hear this music. "You Can't Resist It" by Lyle Lovett,if you have ever fallen in love, period. I saw Lyle and Leo Kottke play this song with just 2 acoustic guitars, it was incredible. "The Koln Concert" by Keith Jarrett. I love this thread. I haven't finished all the responses yet, but I will. It is very informative.

Akino Arai - Furu Platinum - Orange Noel -
Japanese Female vocalist with the prettiest voice in
the world, and the best arrangements ever.

Most of her career has been spent singing theme music
for anime movies, and TV show theme songs.

Most excellent choice Quirkasaurus.
How much BoTox do you think she needs to pantomime the anime?

John Williams rendition of Joaquin Rodrigo's Concierto de Aranjuez on RCA Red Seal.

Summertime - Louis and Ella from Porgy and Bess

The look of Love - Dusty Springfield from Casino Royale (Burt Bacharach)

Besides the three I would like to mention some others which I had great difficulty in putting it in runners up.

Fur Elise - Beethoven

Moonlight Sonata - Beethoven Radu Lupo, Israel Sypmphony Orchestra

The four seasons - Vivaldi - Joseph Silverstien, Seiji Ozawa, Boston Symphony Orchestra

Beethoven's 9th Symphony - Seiji Ozawa on Telarc

The girl from Ipanema - Antonio Carlos Jobim, from Getz/Gilbarto

Childrens Games - Antonio Carlos Jobim - Stoneflower

Lara's Theme - Maurice Jarre Original Soundtrack from Dr Zhivago

A man and a woman - Francis Lai Original Soundtrack

There are many others but it would not be appropriate from me to compile a huge list here. I hope I am not forgetting some other superb inspirational and soul stiring music.