I agree with Artmaltman... consider your needs.
If lossless is really important, than I'd suggest creating playlists, and managing your CD collection manually. Do you really need access to all 110 CDs at once? Put on as much as you can, and change it up as needed. iTunes is a great management tool for your digital music.
Also, can't remember where I saw it but the 128-bit AAC is actually supposed to sound superior to higher bit-rate AAC.
If lossless is really important, than I'd suggest creating playlists, and managing your CD collection manually. Do you really need access to all 110 CDs at once? Put on as much as you can, and change it up as needed. iTunes is a great management tool for your digital music.
Also, can't remember where I saw it but the 128-bit AAC is actually supposed to sound superior to higher bit-rate AAC.