i recommend a tube preamp, especially w/solid-state amp. if ya listen to cd, it will also make it much less fatigueing. personally, i really like my melos music director preamp (latest version of the ma-333). this can be had for way less than $5k, used.
re: speakers, i'd suggest trying newform research r645's or nhb645's check out the reviews on audioreview, & check out the www. i'm saving for these - i think they will be a steal at the price, even if purchased new. if not, there's a 30-day in-home trial, yure only out return-shipping if they're not for you...