Best high-end headphones with noice cancellation ...

IEA, noise cancelling no matter what the brand are junk and I have had them all. Bose, B&W, Sony....... pre Pandemic I flew every week. 

If you are using iPhone then Apple’s new headphone Air pod Max would be a good choice I never hear them but do have there AirPod Pro. And to my ears the noise cancellation is about the best that’s out there and nothing tops there transparency mode. What I use is the Sony wi1000xm2 and there pretty good sounding earphones, but in transparency mode there not in the same class as apple.

Hello! For me, BOSE and SONY headphones are the best in sound quality and design.

Build quality on the Sony WH-1000XM4 is poor.  My pair’s headband broke after a year of moderate daily usage.